Inactivation of Tetracycline with Sodium Borohydride

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Inactivation of Tetracycline with Sodium Borohydride.

Recently we reported on the rapid inactivation of tetracycline by use of cupric-morpholine complex (Kaplan, Lannon, and Buckwalter, J. Pharm. Sci., 64, 163, 1965). This degradation procedure is used as part of an assay technique for kanamycin in the presence of tetracycline. We have since found that sodium borohydride (Metal Hydrides Inc., Beverly, Mass.) can substitute for cupric-morpholine co...

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ژورنال

عنوان ژورنال: Applied Microbiology

سال: 1965

ISSN: 0003-6919

DOI: 10.1128/aem.13.3.505-505.1965